Cellular and Pharmacogenetics Foundation of Synergistic Interaction of Pemetrexed and Gemcitabine in Human Non–Small-Cell Lung Cancer Cells

Randomized Phase III Trial of Pemetrexed Versus Docetaxel in Patients With Non–Small-Cell Lung Cancer Previously Treated With Chemotherapy

Nasser H. Hanna, Frances A. Shepherd, Frank V. Fossella et al. · Journal of Clinical Oncology · 2004 · 2.4K citations · Full text

Medicine, Oncology, Pharmacology +15

Cisplatin-Based Adjuvant Chemotherapy in Patients with Completely Resected Non–Small-Cell Lung Cancer

New England Journal of Medicine · 2004 · 2.4K citations

Medicine, Oncology, Chemotherapy +14

Functional nucleoside transporters are required for gemcitabine influx and manifestation of toxicity in cancer cell lines.

John R. Mackey, Rajam S. Mani, M Selner et al. · PubMed · 1998 · 605 citations

Medicine, Oncology, Pharmacology +14

LY231514, a pyrrolo[2,3-d]pyrimidine-based antifolate that inhibits multiple folate-requiring enzymes.

C Shih, V J Chen, Lynn S. Gossett et al. · PubMed · 1997 · 565 citations

Medicine, Medicinal Chemistry, Pharmacology +14

Computerized Quantitation of Synergism and Antagonism of Taxol, Topotecan, and Cisplatin Against Human Teratocarcinoma Cell Growth: a Rational Approach to Clinical Protocol Design

Ting‐Chao Chou, Robert J. Motzer, Yanli Tong et al. · JNCI Journal of the National Cancer Institute · 1994 · 527 citations

Medicine, Oncology, Pharmacology +13