Concepedia

Population pharmacokinetic modelling of aripiprazole and its active metabolite, dehydroaripiprazole, in psychiatric patients

Jung‐Ryul Kim, Hyo‐Bum Seo, Joo‐Youn Cho, Do‐Hyung Kang, Yong Ku Kim, Won‐Myong Bahk, Kyung‐Sang Yu, Sang‐Goo Shin, Jun Soo Kwon, In‐Jin Jang

British Journal of Clinical Pharmacology · 2008 · 52 citations · 18 references

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Abstract

This population pharmacokinetic model provided an adequate fit to the data for both aripiprazole and dehydroaripiprazole in psychiatric patients. The usefulness of CYP genotyping as an aid to select the starting dose should be further investigated.

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18

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Fuji Yokoi · Neuropsychopharmacology · 2002 · 309 citations · Full text

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