The Revised Human Liver Cytochrome P450 “Pie”: Absolute Protein Quantification of CYP4F and CYP3A Enzymes Using Targeted Quantitative Proteomics

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

Life Sciences, Biochemistry, Chemistry +8

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

Medicine, Biochemistry, Pharmacology +15

THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”

Mary F. Paine, Heather L. Hart, Shana S. Ludington et al. · Drug Metabolism and Disposition · 2006 · 874 citations

Medicine, Biochemistry, Pharmacology +12

CYP4F2 genetic variant alters required warfarin dose

Michael D. Caldwell, Tarif Awad, Julie A. Johnson et al. · Blood · 2008 · 522 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +11

Quantitative Atlas of Membrane Transporter Proteins: Development and Application of a Highly Sensitive Simultaneous LC/MS/MS Method Combined with Novel In-silico Peptide Selection Criteria

Junichi Kamiie, Sumio Ohtsuki, Ryo Iwase et al. · Pharmaceutical Research · 2008 · 479 citations

Life Sciences, Biochemistry, Molecular Biology +12