Post-mortem SNP analysis of CYP2D6 gene reveals correlation between genotype and opioid drug (tramadol) metabolite ratios in blood

Cytochrome P450 2D6 variants in a Caucasian population: allele frequencies and phenotypic consequences.

Christoph Sachse, Jürgen Brockmöller, Steffen Bauer et al. · PubMed · 1997 · 979 citations

Medicine, Genetics, Pharmacology +17

Nomenclature for human CYP2D6 alleles

Ann K. Daly, Jürgen Brockmöller, Franck Broly et al. · Pharmacogenetics · 1996 · 400 citations

Life Sciences, Genetics, Molecular Genetics +13

Polymorphism of the cytochrome P450 CYP2D6 gene in a European population: characterization of 48 mutations and 53 alleles, their frequencies and evolution

Delphine Marez, Maryline Legrand, N. Sabbagh et al. · Pharmacogenetics · 1997 · 378 citations

Life Sciences, Genetics, Molecular Genetics +15

Detection of the poor metabolizer-associated CYP2D6(D) gene deletion allele by long-PCR technology

Vidar M. Steen, Ole A. Andreassen, Ann K. Daly et al. · Pharmacogenetics · 1995 · 243 citations

Medicine, Genetics, Pharmacology +16

Ultrarapid metabolizers of debrisoquine: Characterization and PCR‐based detection of alleles with duplication of the <i>CYP2D6</i> gene

Roger Løvlie, Ann K. Daly, Anders Molven et al. · FEBS Letters · 1996 · 195 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14