Concepedia

Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients

Johannes Sch�ller, Jim Cassidy, Étienne Dumont, Brigitte Roos, Ludger Banken, Kazushige Mori, Bruno Reigner, Masahiro Utoh, E. Weidekamm, Sarah Durston

Cancer Chemotherapy and Pharmacology · 2000 · 666 citations · 12 references

DOI

Concepts

References

12

Design of a novel oral fluoropyrimidine carbamate, capecitabine, which generates 5-fluorouracil selectively in tumours by enzymes concentrated in human liver and cancer tissue

Masanori Miwa, Masako Ura, M Nishida et al. · European Journal of Cancer · 1998 · 1.2K citations

, , +12

Clinicopathologic and Prognostic Significance of an Angiogenic Factor, Thymidine Phosphorylase, in Human Colorectal Carcinoma

Y. Takebayashi, Shin‐ichi Akiyama, Suminori Akiba et al. · JNCI Journal of the National Cancer Institute · 1996 · 366 citations

, , +14

Phase I and pharmacologic study of intermittent twice-daily oral therapy with capecitabine in patients with advanced and/or metastatic cancer.

Melanie Mackean, André Planting, Chris Twelves et al. · Journal of Clinical Oncology · 1998 · 268 citations

, , +15

Preliminary studies of a novel oral fluoropyrimidine carbamate: capecitabine.

Daniel R. Budman, Neal J. Meropol, Bruno Reigner et al. · Journal of Clinical Oncology · 1998 · 259 citations

, , +17

Expression of platelet‐derived endothelial cell growth factor/thymidine phosphorylase in human breast cancer

Masakazu Toi, Seigo Hosnina, Tadaaki Taniguchi et al. · International Journal of Cancer · 1995 · 162 citations

, , +10