Preferential activation of capecitabine in tumor following oral administration to colorectal cancer patients

Johannes Sch�ller, Jim Cassidy, Étienne Dumont, +7

Cancer Chemotherapy and Pharmacology

OncologyChemoprevention StrategyGastrointestinal OncologyMedicineColorectal Cancer +8

Single-Ascending-Dose Pharmacokinetics and Safety of the Novel Broad-Spectrum Antifungal Triazole BAL4815 after Intravenous Infusions (50, 100, and 200 Milligrams) and Oral Administrations (100, 200, and 400 Milligrams) of Its Prodrug, BAL8557, in Healthy Volunteers

Anne Schmitt‐Hoffmann, Brigitte Roos, M. Heep, +4

Antimicrobial Agents and Chemotherapy

Effect of food on the pharmacokinetics of capecitabine and its metabolites following oral administration in cancer patients.

Bruno Reigner, Jaco J. Verweij, Luc Dirix, +8

PubMed

NutritionChemoprevention StrategyFood IntakePathologyOral Administration +15

Effect of hepatic dysfunction due to liver metastases on the pharmacokinetics of capecitabine and its metabolites.

Chris Twelves, Rob Glynne‐Jones, Jim Cassidy, +7

PubMed

Hepatic DysfunctionChemoprevention StrategyPathologyPharmacotherapyTumor Biology +20

Multiple-Dose Pharmacokinetics and Safety of the New Antifungal Triazole BAL4815 after Intravenous Infusion and Oral Administration of Its Prodrug, BAL8557, in Healthy Volunteers

Anne Schmitt‐Hoffmann, Brigitte Roos, J. Maares, +4

Antimicrobial Agents and Chemotherapy

Effect of renal impairment on the pharmacokinetics and tolerability of capecitabine (Xeloda) in cancer patients

Christopher Poole, J. Gardiner, Chris Twelves, +7

Cancer Chemotherapy and Pharmacology

UrologyMedicineMetronomic TherapyPharmacologyPharmacotherapy +6

Single-Dose Pharmacokinetics and Safety of a Novel Broad-Spectrum Cephalosporin (BAL5788) in Healthy Volunteers

Anne Schmitt‐Hoffmann, Brigitte Roos, Michael Schleimer, +6

Antimicrobial Agents and Chemotherapy

Therapeutic Drug MonitoringSteady StateHealth SciencesAntimicrobial SusceptibilityHealthy Volunteers +13

Plasma concentrations in pyrimethamine and sulfadoxine and evaluation of pharmacokinetic data by computerized curve fitting.

E. Weidekamm, Helene Plozza-Nottebrock, I. Forgò, +1

PubMed

Plasma Concentration ProfilesPhysiologically-based Pharmacokinetic ModelingBioanalysisAnalytical ChemistryToxicology +14

Single- and multiple-dose pharmacokinetics of fleroxacin, a trifluorinated quinolone, in humans

E. Weidekamm, Renée Portmann, Katja Suter, +3

Antimicrobial Agents and Chemotherapy

UrologyRenal EliminationRo 23-6240MedicineAntibiotic Adjuvant +9

The study of lipid-protein interactions in membranes by fluorescent probes

Donald F. H. Wallach, E. Ferber, D. Selin, +2

Biochimica et Biophysica Acta (BBA) - Biomembranes

Proteinlipid InteractionBiochemistryMembrane SystemLipid MovementLipid-protein Interactions +1