Preparation and characterization of a thrombin inhibitor grafted polyethersulfone blending membrane with improved antithrombotic property

Direct Thrombin Inhibitors

Marcello Di Nisio, Saskia Middeldorp, Harry R. Büller · New England Journal of Medicine · 2005 · 652 citations · Full text

Medicine, Biochemistry, Pharmacology +17

The Pharmacokinetics and Pharmacodynamics of Argatroban: Effects of Age, Gender, and Hepatic or Renal Dysfunction

Suzanne K. Swan, Marcie J. Hursting · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · 2000 · 371 citations

Pharmacy, Pharmacokinetics, Pharmacology +15

Selective inhibition of thrombin by (2R,4R)-4-methyl-1-[N2-[1,2,3,4-tetrahydro-8-quinolinyl)sulfonyl]-L-arginyl]-2-piperidinecarboxylic acid

Ryoji Kikumoto, Y Tamao, Toru Tezuka et al. · Biochemistry · 1984 · 310 citations

Medicine, Pharmacology, Biochemical Pharmacology +8

Crystallographic analysis at 3.0-A resolution of the binding to human thrombin of four active site-directed inhibitors.

David W. Banner, Paul Hadváry · Journal of Biological Chemistry · 1991 · 294 citations · Full text

Life Sciences, Biology, Biophysics +14

Potent inhibition of thrombin by the newly synthesized arginine derivative No. 805. The importance of stereo-structure of its hydrophobic carboxamide portion

Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto et al. · Biochemical and Biophysical Research Communications · 1981 · 246 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11