Ryoji Kikumoto

Selective inhibition of thrombin by (2R,4R)-4-methyl-1-[N2-[1,2,3,4-tetrahydro-8-quinolinyl)sulfonyl]-L-arginyl]-2-piperidinecarboxylic acid

Ryoji Kikumoto, Y Tamao, Toru Tezuka et al. · Biochemistry · 1984 · 310 citations

Potent inhibition of thrombin by the newly synthesized arginine derivative No. 805. The importance of stereo-structure of its hydrophobic carboxamide portion

Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto et al. · Biochemical and Biophysical Research Communications · 1981 · 246 citations

Medicinal Chemistry, Biochemistry, Natural Sciences +11

MCI–9042, a New Antiplatelet Agent Is a Selective S2-Serotonergic Receptor Antagonist

Hiroto Hara, Masanori Osakabe, A Kitajima et al. · Thrombosis and Haemostasis · 1991 · 121 citations

Inflammation, Molecular Pharmacology, Thrombopoiesis +15

Effect of a Selective Thrombin Inhibitor MCI-9038 on Fibrinolysis In Vitro and In Vivo

Y Tamao, Toshihiro Yamamoto, Ryoji Kikumoto et al. · Thrombosis and Haemostasis · 1986 · 63 citations

Immunology, Pharmacotherapy, Biomedical Engineering +19

Thrombin inhibitors. 3. Carboxyl-containing amide derivatives of N.alpha.-substituted L-arginine

Ryoji Kikumoto, Y Tamao, Kazuo Ohkubo et al. · Journal of Medicinal Chemistry · 1980 · 51 citations · Full text