Selective inhibition of thrombin by (2R,4R)-4-methyl-1-[N2-[1,2,3,4-tetrahydro-8-quinolinyl)sulfonyl]-L-arginyl]-2-piperidinecarboxylic acid

Ryoji Kikumoto, Y Tamao, Toru Tezuka, +5

Biochemistry

Potent inhibition of thrombin by the newly synthesized arginine derivative No. 805. The importance of stereo-structure of its hydrophobic carboxamide portion

Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto, +6

Biochemical and Biophysical Research Communications

Medicinal ChemistryBiochemistryNatural SciencesMedicineBioconjugation +9

Thrombin inhibitors. 3. Carboxyl-containing amide derivatives of N.alpha.-substituted L-arginine

Ryoji Kikumoto, Y Tamao, Kazuo Ohkubo, +4

Journal of Medicinal Chemistry

Thrombin inhibitors. 2. Amide derivatives of N.alpha.-substituted L-arginine

Ryoji Kikumoto, Y Tamao, Kazuo Ohkubo, +5

Journal of Medicinal Chemistry

ThrombosisMedicinal ChemistryPharmaceutical ScienceBiochemistryMedicine +12

Thrombin inhibitors. 1. Ester derivatives of N.alpha.-(arylsulfonyl)-L-arginine

Shosuke Okamoto, Kiyokatsu Kinjo, Akiko Hijikata, +4

Journal of Medicinal Chemistry

ThrombosisMedicinal ChemistryThrombin InhibitorsBiochemistryChain Length +13

Effect of thrombin on plasminogen activator release from isolated perfused dog leg

Hiromichi Kitaguchi, Akiko Hijikata, Mari Hirata

Thrombosis Research

Animal PhysiologyThrombosisPlasminogen Activator ReleaseThrombopoiesisPerfused Dog Leg +12

Effect of proteases on plasminogen activator release from isolated perfused dog leg

Akiko Hijikata, Mari Hirata, Hiromichi Kitaguchi

Thrombosis Research

Animal PhysiologyPlasminogen Activator ReleaseVeterinary PhysiologyPerfused Dog LegAnimal Science +9

A new series of synthetic thrombin-inhibitors (OM-inhibitors) having extremely potent and selective action

Shosuke Okamoto, Akiko Hijikata, K Ikezawa, +4

Thrombosis Research

ThrombosisMedicinal ChemistryBiochemistryMedicineNatural Sciences +12

A novel series of synthetic thrombin-inhibitors having extremely potent and highly selective action.

Shosuke Okamoto, Akiko Hijikata, Kentaro Kinjo, +2

PubMed

Molecular PharmacologyMedicinal ChemistryThrombosisNovel SeriesBiochemistry +12

In vitro and in vivo studies of a new series of synthetic thrombin-inhibitors (OM-inhibitors)

Akiko Hijikata, Shosuke Okamoto, Etsuko Mori, +5

Thrombosis Research

ThrombopoiesisThrombosisVivo StudiesBiochemistryBlood Platelet +11