Akiko Hijikata

Selective inhibition of thrombin by (2R,4R)-4-methyl-1-[N2-[1,2,3,4-tetrahydro-8-quinolinyl)sulfonyl]-L-arginyl]-2-piperidinecarboxylic acid

Ryoji Kikumoto, Y Tamao, Toru Tezuka et al. · Biochemistry · 1984 · 310 citations

Medicine, Pharmacology, Biochemical Pharmacology +8

Potent inhibition of thrombin by the newly synthesized arginine derivative No. 805. The importance of stereo-structure of its hydrophobic carboxamide portion

Shosuke Okamoto, Akiko Hijikata, Ryoji Kikumoto et al. · Biochemical and Biophysical Research Communications · 1981 · 246 citations

Pharmacy, Medicinal Chemistry, Pharmacology +11

Thrombin inhibitors. 3. Carboxyl-containing amide derivatives of N.alpha.-substituted L-arginine

Ryoji Kikumoto, Y Tamao, Kazuo Ohkubo et al. · Journal of Medicinal Chemistry · 1980 · 51 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +9

Thrombin inhibitors. 2. Amide derivatives of N.alpha.-substituted L-arginine

Ryoji Kikumoto, Y Tamao, Kazuo Ohkubo et al. · Journal of Medicinal Chemistry · 1980 · 50 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Thrombin inhibitors. 1. Ester derivatives of N.alpha.-(arylsulfonyl)-L-arginine

Shosuke Okamoto, Kiyokatsu Kinjo, Akiko Hijikata et al. · Journal of Medicinal Chemistry · 1980 · 49 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10