Concepedia

Crohn’s-like Colitis in a Patient with Immunodeficiency Associated with a Defect in Expression of Inducible Costimulator

Jonas Mudter, Stefan Wirtz, Benno Weigmann, Imke Tiede, Ingrid Tubbe, Peter R. Galle, Hans A. Lehr, Markus F. Neurath

Digestive Diseases and Sciences · 2006 · 10 citations · 16 references

DOI

Concepts

References

16

Targeted Disruption of the Stat1 Gene in Mice Reveals Unexpected Physiologic Specificity in the JAK–STAT Signaling Pathway

Marco Antonio Meraz‐Ríos, J. Michael White, Kathleen C. F. Sheehan et al. · Cell · 1996 · 1.7K citations · Full text

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ICOS is an inducible T-cell co-stimulator structurally and functionally related to CD28

Andreas Hutloff, Anna‐Maria Dittrich, Katja C. Beier et al. · Nature · 1999 · 1.5K citations

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Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: Evidence in Crohn disease and experimental colitis in vivo

Raja Atreya, Jonas Mudter, Susetta Finotto et al. · Nature Medicine · 2000 · 1.3K citations

, , +17

T-bet is a STAT1-induced regulator of IL-12R expression in naïve CD4+ T cells

Maryam Afkarian, John R. Šedý, Jianfei Yang et al. · Nature Immunology · 2002 · 1K citations

, , +15

Homozygous loss of ICOS is associated with adult-onset common variable immunodeficiency

Bodo Grimbacher, Andreas Hutloff, Michael Schlesier et al. · Nature Immunology · 2003 · 730 citations

, , +14