Concepedia

Synthesis of the first sulfur-35-labeled hERG radioligand

Conrad E. Raab, John W. Butcher, Thomas Connolly, Jerzy Karczewski, Nathan X. Yu, Steven J. Staskiewicz, Nigel J. Liverton, Dennis Dean, David G. Melillo

Bioorganic & Medicinal Chemistry Letters · 2006 · 26 citations · 13 references

DOI

Concepts

References

13

A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel

Michael C. Sanguinetti, Changan Jiang, Mark Curran et al. · Cell · 1995 · 2.4K citations · Full text

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Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents.

Michael C. Sanguinetti, Nancy K. Jurkiewicz · The Journal of General Physiology · 1990 · 1.5K citations · Full text

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HERG, a Human Inward Rectifier in the Voltage-Gated Potassium Channel Family

Matthew C. Trudeau, Jeffrey W. Warmke, Barry Ganetzky et al. · Science · 1995 · 1.2K citations

, , +17

A family of potassium channel genes related to eag in Drosophila and mammals.

Jeffrey W. Warmke, Barry Ganetzky · Proceedings of the National Academy of Sciences · 1994 · 982 citations

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Properties of HERG Channels Stably Expressed in HEK 293 Cells Studied at Physiological Temperature

Zhengfeng Zhou, Qiuming Gong, Bin Ye et al. · Biophysical Journal · 1998 · 735 citations · Full text

, , +16