Concepedia
Drug Metabolism and Disposition · 2012 · 52 citations · 27 references
Life SciencesMolecular BiologyPharmacologyGene ExpressionGene RegulationMolecular PharmacologyCyclin-dependent KinasesEnzyme InductionReceptor RegulationConstitutive Androstane Receptor SignalingCyclin-dependent Kinase InhibitorsPregnane X Receptor Signaling
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The coregulator exchange in transcriptional functions of nuclear receptors
Christopher K. Glass, Michael G. Rosenfeld · Genes & Development · 2000 · 2.2K citations · Full text
Life Sciences, Cell Biology, Molecular Biology +16
Biochemical and Cellular Effects of Roscovitine, a Potent and Selective Inhibitor of the Cyclin‐Dependent Kinases cdc2, cdk2 and cdk5
Laurent Meijer, Annie Borgne, Odile Mulner et al. · European Journal of Biochemistry · 1997 · 1.4K citations
Medicine, Cancer Biology, Oncology +15
The Phenobarbital Response Enhancer Module in the Human Bilirubin Udp–Glucuronosyltransferase Ugt1a1 Gene and Regulation by the Nuclear Receptor Car
Junko Sugatani, Hiroyuki Kojima, Akiko Ueda et al. · Hepatology · 2001 · 378 citations · Full text
Life Sciences, Molecular Biology, Pharmacology +16
Common Human UGT1A Polymorphisms and the Altered Metabolism of Irinotecan Active Metabolite 7-Ethyl-10-hydroxycamptothecin (SN-38)
Jean-François Gagné, Valérie Montminy, Patrick Bélanger et al. · Molecular Pharmacology · 2002 · 341 citations
Medicine, Biochemistry, Pharmacology +14
Coactivator Binding Promotes the Specific Interaction Between Ligand and the Pregnane X Receptor
Ryan E. Watkins, Paula R. Davis-Searles, Mill H. Lambert et al. · Journal of Molecular Biology · 2003 · 217 citations
Medicine, Molecular Biology, Pharmacology +16