Concepedia

Ryan E. Watkins

RE

6

Publications

1.4K

Citations

6

H-Index

2001

Active since

Affiliations

GlaxoSmithKline (United States)(Current)

Research Triangle Park Foundation

University of North Carolina at Chapel Hill

GlaxoSmithKline (Netherlands)

Ryan E. Watkins is an author at GlaxoSmithKline (United States) specializing in medicine, signal transduction, and pharmacology.

Top concepts

MedicineBiochemistryPharmacologySignal TransductionDrug DiscoveryChemical BiologyNatural SciencesMolecular BiologyDevelopmental BiologyMolecular Pharmacology

Publications per year

2001–2008

6

Publications

6

The Human Nuclear Xenobiotic Receptor PXR: Structural Determinants of Directed Promiscuity

Ryan E. Watkins, G. Bruce Wisely, Linda B. Moore et al. · Science · 2001 · 748 citations

Proteinlipid Interaction, Polar Residues, Genetics +21

2.1 Å Crystal Structure of Human PXR in Complex with the St. John's Wort Compound Hyperforin<sup>,</sup>

Ryan E. Watkins, Jodi M. Maglich, Linda B. Moore et al. · Biochemistry · 2003 · 317 citations

Coactivator Binding Promotes the Specific Interaction Between Ligand and the Pregnane X Receptor

Ryan E. Watkins, Paula R. Davis-Searles, Mill H. Lambert et al. · Journal of Molecular Biology · 2003 · 216 citations

Molecular Pharmacology, Pregnane X Receptor, Signal Transduction +8

Structural insights into the promiscuity and function of the human pregnane X receptor.

Ryan E. Watkins, Schroeder M. Noble, Matthew R. Redinbo · PubMed · 2002 · 72 citations

Molecular Regulation, Human Pxr, Gynecology +19

Human PXR Forms a Tryptophan Zipper-Mediated Homodimer

Schroeder M. Noble, Virginia Elaine Carnahan, Linda B. Moore et al. · Biochemistry · 2006 · 62 citations · Full text

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