Access to Imidazo[1,2‐<i>a</i>]imidazolin‐2‐ones and Functionalization through Suzuki–Miyaura Cross‐Coupling Reactions

Abstract

Abstract We report herein a synthetic pathway to new 6(5)‐bromo‐5(6)‐methylimidazo[1,2‐ a ]imidazolin‐2‐ones. The synthetic potential of these scaffolds was demonstrated by displacing bromine by Suzuki–Miyaura cross‐coupling reactions. A large panel of boronic acids (aryl, heteroaryl or vinyl) could easily be introduced, giving access to a large and diversified library of 6(5)‐substituted 5(6)‐methylimidazo[1,2‐ a ]imidazolin‐2‐ones.