Role of a Potent Inhibitory Monoclonal Antibody to Cytochrome P-450 3A4 in Assessment of Human Drug Metabolism

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

Isolation of pure IgG1, IgG2a and IgG2b immunoglobulins from mouse serum using protein A-Sepharose

Peter L. Ey, Stephen J. Prowse, C. R. Jenkin · Immunochemistry · 1978 · 2.7K citations

Immunohematology, Immunocytochemical Technique, Allergy +13

Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1

Raimund M. Peter, Ronald Boecker, Philippe Beaune et al. · Chemical Research in Toxicology · 1990 · 535 citations

Cytochrome P450 2E1 and 2A6 enzymes as major catalysts for metabolic activation of <i>N</i>-nitrosodialkylamines and tobacco-related nitrosamines in human liver microsomes

Hiroshi Yamazaki, Yukiharu Inui, Chul‐Ho Yun et al. · Carcinogenesis · 1992 · 394 citations

Selective biotransformation of taxol to 6 alpha-hydroxytaxol by human cytochrome P450 2C8.

Atiqur Rahman, Ken Korzekwa, James Grogan et al. · PubMed · 1994 · 391 citations

Pharmaceutical Science, Pharmaceutical Chemistry, Aldehyde Dehydrogenase +15