Accelerated Atherosclerosis in <i> Apoe <sup>−/−</sup> </i> Mice Heterozygous for the Insulin Receptor and the Insulin Receptor Substrate-1 - Concepedia

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Accelerated Atherosclerosis in <i> Apoe <sup>−/−</sup> </i> Mice Heterozygous for the Insulin Receptor and the Insulin Receptor Substrate-1

DOI Full Paper Access

40

Citations

31

References

2011

Year

Elena Galkina, Matthew Butcher, Susanna R. Keller, Matthew Goff, Anthony C. Bruce, Hong Pei, Ian J. Sarembock, John M. Sanders, Melissa H. Nagelin, Suseela Srinivasan,

Arteriosclerosis Thrombosis and Vascular Biology

Abstract

These results demonstrate that defective insulin signaling is involved in accelerated atherosclerosis in Insr(+/-)Irs1(+/-)Apoe(-/-) mice by promoting vascular dysfunction and inflammation.

References

	Year	Citations

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