Timothy J. McCabe

Regulation of endothelium-derived nitric oxide production by the protein kinase Akt

David Fulton, Jean‐Philippe Gratton, Timothy J. McCabe et al. · Nature · 1999 · 2.6K citations

Life Sciences, Cell Biology, Molecular Biology +10

Enhanced Electron Flux and Reduced Calmodulin Dissociation May Explain “Calcium-independent” eNOS Activation by Phosphorylation

Timothy J. McCabe, David Fulton, Linda J. Roman et al. · Journal of Biological Chemistry · 2000 · 386 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +16

Domain Mapping Studies Reveal That the M Domain of hsp90 Serves as a Molecular Scaffold to Regulate Akt-Dependent Phosphorylation of Endothelial Nitric Oxide Synthase and NO Release

Jason Fontana, David Fulton, Yan Chen et al. · Circulation Research · 2002 · 343 citations

Life Sciences, Biochemistry, Cell Biology +14

Reconstitution of an Endothelial Nitric-oxide Synthase (eNOS), hsp90, and Caveolin-1 Complex in Vitro

Jean‐Philippe Gratton, Jason Fontana, Daniel O’Connor et al. · Journal of Biological Chemistry · 2000 · 326 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10

Acidic Hydrolysis as a Mechanism for the Cleavage of the Glu298 → Asp Variant of Human Endothelial Nitric-oxide Synthase

Todd A. Fairchild, David Fulton, Jason Fontana et al. · Journal of Biological Chemistry · 2001 · 176 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +10