Characterization of Angiotensin II Molecular Determinants Involved in AT1 Receptor Functional Selectivity

Multiple sequence alignment with hierarchical clustering

F. Corpet · Nucleic Acids Research · 1988 · 5.4K citations · Full text

Life Sciences, Bioinformatics, Biology +14

Independent β-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2

Huijun Wei, Seungkirl Ahn, Sudha K. Shenoy et al. · Proceedings of the National Academy of Sciences · 2003 · 669 citations · Full text

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Differential Kinetic and Spatial Patterns of β-Arrestin and G Protein-mediated ERK Activation by the Angiotensin II Receptor

Seungkirl Ahn, Sudha K. Shenoy, Huijun Wei et al. · Journal of Biological Chemistry · 2004 · 496 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +15

A Simple Method for Quantifying Functional Selectivity and Agonist Bias

Terry Kenakin, Christian Watson, Vanessa Muniz‐Medina et al. · ACS Chemical Neuroscience · 2011 · 486 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Selectively Engaging β-Arrestins at the Angiotensin II Type 1 Receptor Reduces Blood Pressure and Increases Cardiac Performance

Jonathan D. Violin, Scott M. DeWire, Dennis S. Yamashita et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 370 citations

Medicine, Cardiology, Pharmacology +17