Angewandte Chemie International Edition · 2010 · 63 citations · 38 references
PharmacyMedicinal ChemistryPharmacologyApoptosisDrug DiscoverySynthetic Medicinal ChemistryApoptosis PharmacologyCombinatorial SynthesisConjugation ReactionsAnti-apoptotic AgentsApoptosis-inducing FactorDiversity-oriented Total SynthesisNatural Product Total SynthesisTotal Synthesis-derived Analogues
In a one-step conversion, commercially available or known compounds are connected to form myrtucommulone A, an anti-inflammatory and apoptosis-inducing substance from the common myrtle Myrtus communis (see scheme). This strategy can be used, as well to prepare myrtucommulone libraries.
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A short history of<i>SHELX</i>
George M. Sheldrick · Acta Crystallographica Section A Foundations of Crystallography · 2007 · 87.4K citations · Full text