Concepedia

Licofelone Suppresses Prostaglandin E2 Formation by Interference with the Inducible Microsomal Prostaglandin E2 Synthase-1

Andreas Koeberle, Ulf Siemoneit, Ulrike Bühring, Hinnak Northoff, Stefan Laufer, Wolfgang Albrecht, Oliver Werz

Journal of Pharmacology and Experimental Therapeutics · 2008 · 165 citations · 29 references

DOI

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29

Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase.

Jane A. Mitchell, Pravit Akarasereenont, Christoph Thiemermann et al. · Proceedings of the National Academy of Sciences · 1993 · 1.7K citations

, , +9

COX-2 inhibitors

The Lancet · 1999 · 1.2K citations

Identification of human prostaglandin E synthase: A microsomal, glutathione-dependent, inducible enzyme, constituting a potential novel drug target

Per‐Johan Jakobsson, Staffan Thorén, Ralf Morgenstern et al. · Proceedings of the National Academy of Sciences · 1999 · 995 citations

, , +14

Regulation of Prostaglandin E2 Biosynthesis by Inducible Membrane-associated Prostaglandin E2 Synthase That Acts in Concert with Cyclooxygenase-2

Makoto Murakami, Hiroaki Naraba, Toshihiro Tanioka et al. · Journal of Biological Chemistry · 2000 · 968 citations · Full text

, , +15

Impaired inflammatory and pain responses in mice lacking an inducible prostaglandin E synthase

Catherine E. Trebino, Jeffrey L. Stock, Colleen P. Gibbons et al. · Proceedings of the National Academy of Sciences · 2003 · 547 citations · Full text

, , +17