Variable Degree of Alternative Complement Pathway–Mediated Hemolysis in Indian Visceral Leishmaniasis Induced by Differential Expression of 9‐<i>O–</i>Acetylated Sialoglycans

Abstract

The 9-O-AcSGs expressed on erythrocytes from patients with VL are potent complement activators, causing enhanced hemolysis via activation of the alternative complement pathway, and may account for the anemia that is a common manifestation of VL.