Concepedia

Quercetin Potentiates Doxorubicin Mediated Antitumor Effects against Liver Cancer through p53/Bcl-xl

Guanyu Wang, Jiawei Zhang, Luying Liu, Sherven Sharma, Qinghua Dong

PLoS ONE · 2012 · 149 citations · 38 references

DOIFull text

Open access

Abstract

These results indicate that quercetin potentiated the antitumor effects of DOX on liver cancer cells while protecting normal liver cells. Therefore, the development of quercetin may be beneficial in a combined treatment with DOX for increased therapeutic efficacy against liver cancer.

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