Apocynin, a plant-derived, cartilage-saving drug, might be useful in the treatment of rheumatoid arthritis

Abstract

Apocynin in vitro inhibits inflammation-mediated cartilage destruction without having adverse effects on cartilage. The latter may be an advantage of apocynin over many other non-steroidal anti-inflammatory drugs. Therefore, apocynin might have an added beneficial effect in protecting RA patients from joint destruction.