Microsatellite instability of selective target genes in HNPCC-associated colon adenomas

Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis

Yurij Ionov, Miguel A. Peinado, Sergei Malkhosyan et al. · Nature · 1993 · 2.7K citations

Medicine, Genetics, Molecular Genetics +17

New clinical criteria for hereditary nonpolyposis colorectal cancer (HNPCC, Lynch syndrome) proposed by the International Collaborative Group on HNPCC☆

Hans F. A. Vasen, Peter H. Watson, Jukka‐Pekka Mecklin et al. · Gastroenterology · 1999 · 2.5K citations · Full text

Life Sciences, Genetics, Oncology +17

Genetic instability in colorectal cancers

Christoph Lengauer, Kenneth W. Kinzler, Bert Vogelstein · Nature · 1997 · 2K citations

Medicine, Genetics, Molecular Genetics +14

Intracellular Adenosine Triphosphate (ATP) Concentration: A Switch in the Decision Between Apoptosis and Necrosis

Marcel Leist, Barbara Single, Anna Federica Castoldi et al. · The Journal of Experimental Medicine · 1997 · 1.9K citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Somatic Frameshift Mutations in the <i>BAX</i> Gene in Colon Cancers of the Microsatellite Mutator Phenotype

Nicholas J. Rampino, Hiroyuki Yamamoto, Yurij Ionov et al. · Science · 1997 · 1.3K citations

Life Sciences, Genetics, Oncology +17