Lab on a Chip · 2010 · 155 citations · 19 references
EngineeringBioengineeringMechanical EngineeringMicroelectromechanical SystemsMicrofabricationPhotonicsMicrofabrication ProcessesMicrofluidic Device FabricationMicrofluidic DevicesMicrofluidic SystemsMicrofluidicsMicromachining3D MicrofluidicsMicrochannel FabricationMicrofluidic FabricationMicrofluidic MixingMicromixersMicromixingNumerical SimulationStereolithography
In this study, we report a neo-conceptive three-dimensionally (3D) crossing manifold micromixer (CMM) embedded in microchannel. Fabricated by sequential processes of photolithography and two photon absorption stereolithography, this leads to a microfluidic system with a built-in micromixer in a site controlled manner. The effectiveness of CMM is investigated numerically and experimentally. Through the numerical simulation, it is estimated that a high mixing ratio of 90% can be obtained even in a channel length shorter than five times the channel width. This compares well with the conventional passive type of micromixers that have a gradual increase in mixing efficiency with the length of the channel. Furthermore, the mixing performance of the realized CMM built-in microchannel is observed by confocal microscopy.
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Chaotic Mixer for Microchannels
Abraham D. Stroock, Stephan K. W. Dertinger, Armand Ajdari et al. · Science · 2002 · 3.4K citations
Passive mixing in a three-dimensional serpentine microchannel
Ruize Liu, Mark A. Stremler, Kendra V. Sharp et al. · Journal of Microelectromechanical Systems · 2000 · 1.2K citations