Concepedia

Polymer–paclitaxel conjugates based on disulfide linkers for controlled drug release

Wulian Chen, Luqman Ali Shah, Yuan Li, Mohammad Siddiq, Jianhua Hu, Dong Yang

RSC Advances · 2014 · 33 citations · 35 references

DOI

Concepts

Abstract

Controlled drug delivery system based on hydrophilic diblock copolymer covalently linked paclitaxel (PTX) <italic>via</italic> a disulfide linker.

References

35

A new concept for macromolecular therapeutics in cancer chemotherapy: mechanism of tumoritropic accumulation of proteins and the antitumor agent smancs.

Yasuhiro Matsumura, Hiroshi Maeda · PubMed · 1986 · 6.8K citations

, , +12

Biodegradable Long-Circulating Polymeric Nanospheres

Ruxandra Gref, Yoshiharu Minamitake, Maria Teresa Peracchia et al. · Science · 1994 · 2.9K citations

, , +17

Design of Environment‐Sensitive Supramolecular Assemblies for Intracellular Drug Delivery: Polymeric Micelles that are Responsive to Intracellular pH Change

Younsoo Bae, Shigeto Fukushima, Atsushi Harada et al. · Angewandte Chemie International Edition · 2003 · 1.3K citations

, , +17

Synthesis of Molecular Brushes by “Grafting onto” Method:  Combination of ATRP and Click Reactions

Haifeng Gao, Krzysztof Matyjaszewski · Journal of the American Chemical Society · 2007 · 573 citations

, , +17

Polymeric Conjugates for Drug Delivery

Nate Larson, Hamidreza Ghandehari · Chemistry of Materials · 2012 · 571 citations · Full text

, , +17