Concepedia

Characterization of mRNA and microRNA in human mast cell‐derived exosomes and their transfer to other mast cells and blood CD34 progenitor cells

Karin M. Ekström, Hadi Valadi, Margareta Sjöstrand, Carina Malmhäll, Apostolos Bossios, Maria Eldh, Jan Lötvall

Journal of Extracellular Vesicles · 2012 · 199 citations · 33 references

DOIFull text

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Abstract

These findings suggest that exosomal shuttle RNA (esRNA) can play a role in the communication between cells, including mast cells and CD34(+) progenitor cells, implying a role in cells maturation process.

References

33

Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

Hadi Valadi, Karin M. Ekström, Apostolos Bossios et al. · Nature Cell Biology · 2007 · 12.6K citations

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Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

Johan Skog, Tom Würdinger, Sjoerd van Rijn et al. · Nature Cell Biology · 2008 · 4.9K citations

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Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

Lydia Alvarez‐Erviti, Yiqi Seow, HaiFang Yin et al. · Nature Biotechnology · 2011 · 4.7K citations

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Combinatorial microRNA target predictions

Azra Krek, Dominic Grün, Matthew N. Poy et al. · Nature Genetics · 2005 · 4.6K citations

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B lymphocytes secrete antigen-presenting vesicles.

Graça Raposo, Hans W. Nijman, Willem Stoorvogel et al. · The Journal of Experimental Medicine · 1996 · 3.4K citations · Full text

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