Concepedia

Kinesin Family Deregulation Coordinated by Bromodomain Protein ANCCA and Histone Methyltransferase MLL for Breast Cancer Cell Growth, Survival, and Tamoxifen Resistance

June X. Zou, Zhijian Duan, Junjian Wang, Alex Sokolov, Jianzhen Xu, Christopher Z. Chen, Jian Jian Li, Hong-Wu Chen

Molecular Cancer Research · 2014 · 213 citations · 47 references

DOIFull text

Open access

Abstract

These findings support the development of novel inhibitors of cancer-associated kinesins and their regulator ANCCA for effective treatment of cancers including tamoxifen-resistant breast cancers.

References

47

An online survival analysis tool to rapidly assess the effect of 22,277 genes on breast cancer prognosis using microarray data of 1,809 patients

Balázs Győrffy, András Lánczky, Aron C. Eklund et al. · Breast Cancer Research and Treatment · 2009 · 4.3K citations · Full text

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The mutational landscape of lethal castration-resistant prostate cancer

Catherine S. Grasso, Yi-Mi Wu, Dan R. Robinson et al. · Nature · 2012 · 2.6K citations

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Genome-wide analysis of estrogen receptor binding sites

Jason S. Carroll, Clifford A. Meyer, Jun S. Song et al. · Nature Genetics · 2006 · 1.4K citations

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Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution

Sohrab P. Shah, Ryan D. Morin, Jaswinder Khattra et al. · Nature · 2009 · 1.1K citations · Full text

Whole-genome analysis informs breast cancer response to aromatase inhibition

Matthew J. Ellis, Li Ding, Dong Shen et al. · Nature · 2012 · 1K citations · Full text