Nephrology Dialysis Transplantation · 2009 · 105 citations · 40 references
In line with previous studies, we observed an overactivated but functionally compromised immune system in patients with end-stage renal failure. It now appears that in this setting, regulation by CD4(+)CD25(bright+)FoxP3(+) T-cells is also impaired.
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Deborah J. Lenschow, Lesley Rhee, Neda Ashourian et al. · Immunity · 2000 · 2K citations · Full text
Control Autoimmune Diabetes, Autoimmune Disease, B7/cd28 Costimulation +9