Concepedia

Pancreatic β Cell Identity Is Maintained by DNA Methylation-Mediated Repression of Arx

Sangeeta Dhawan, Senta Georgia, Shuen-Ing Tschen, Guoping Fan, Anil Bhushan

Developmental Cell · 2011 · 259 citations · 33 references

DOIFull text

Open access

Concepts

References

33

Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors

Kazutoshi Takahashi, Shinya Yamanaka · Cell · 2006 · 26.5K citations · Full text

, , +16

Transcriptional repression by the methyl-CpG-binding protein MeCP2 involves a histone deacetylase complex

Xinsheng Nan, Huck‐Hui Ng, Colin A. Johnson et al. · Nature · 1998 · 3.4K citations

, , +16

Direct conversion of fibroblasts to functional neurons by defined factors

Thomas Vierbuchen, Austin Ostermeier, Zhiping P. Pang et al. · Nature · 2010 · 3K citations

, , +15

Methylated DNA and MeCP2 recruit histone deacetylase to repress transcription

Peter Lloyd Jones, Gert Jan C. Veenstra, Paul A. Wade et al. · Nature Genetics · 1998 · 2.7K citations

, , +10

Adult pancreatic β-cells are formed by self-duplication rather than stem-cell differentiation

Yuval Dor, Juliana Brown, Olga I. Martinez et al. · Nature · 2004 · 2.2K citations

, , +14