Concepedia

LEDGINs inhibit late stage HIV-1 replication by modulating integrase multimerization in the virions

Belete A. Desimmie, Rik Schrijvers, Jonas Demeulemeester, Doortje Borrenberghs, Caroline Weydert, Wannes Thys, Sofie Vets, Barbara Van Remoortel, Johan Hofkens, Jan De Rijck,

Retrovirology · 2013 · 137 citations · 40 references

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References

40

Inhibitors of Strand Transfer That Prevent Integration and Inhibit HIV-1 Replication in Cells

Daria J. Hazuda, Peter J. Felock, Marc Witmer et al. · Science · 2000 · 1.1K citations

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A quantitative assay for HIV DNA integration in vivo

Scott L. Butler, Mark S. Hansen, Frederic D. Bushman · Nature Medicine · 2001 · 701 citations

, , +7

HIV-1 Integrase Forms Stable Tetramers and Associates with LEDGF/p75 Protein in Human Cells

Peter Cherepanov, Goedele N. Maertens, Paul Proost et al. · Journal of Biological Chemistry · 2002 · 693 citations · Full text

A role for LEDGF/p75 in targeting HIV DNA integration

Angela Ciuffi, Manuel Llano, Eric M. Poeschla et al. · Nature Medicine · 2005 · 656 citations

, , +2

Temporal aspects of DNA and RNA synthesis during human immunodeficiency virus infection: evidence for differential gene expression

S Y Kim, Randal A. Byrn, Jerome E. Groopman et al. · Journal of Virology · 1989 · 575 citations · Full text

, , +19