Concepedia

Expansion of Bcr-Abl-Positive Leukemic Stem Cells Is Dependent on Hedgehog Pathway Activation

Christine Dierks, Ronak Beigi, Gui-Rong Guo, Katja Zirlik, Mario Stegert, Paul W. Manley, Christopher Trussell, Annette Schmitt‐Graeff, Klemens Landwerlin, Hendrik Veelken,

Cancer Cell · 2008 · 512 citations · 45 references

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45

Five-Year Follow-up of Patients Receiving Imatinib for Chronic Myeloid Leukemia

Brian Druker, François Guilhot, Stephen G. O’Brien et al. · New England Journal of Medicine · 2006 · 3.5K citations · Full text

, , +13

Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

Chin Chiang, Ying Litingtung, Eric Lee et al. · Nature · 1996 · 3.1K citations

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Induction of Chronic Myelogenous Leukemia in Mice by the P210 <sup> <i>bcr/abl</i> </sup> Gene of the Philadelphia Chromosome

George Q. Daley, Richard A. Van Etten, David Baltimore · Science · 1990 · 2.2K citations · Full text

, , +15

Characterization of AMN107, a selective inhibitor of native and mutant Bcr-Abl

Ellen Weisberg, Paul W. Manley, Werner Breitenstein et al. · Cancer Cell · 2005 · 1.5K citations · Full text

, , +6

Inhibition of Hedgehog signaling by direct binding of cyclopamine to Smoothened

James Chen, Jussi Taipale, Michael K. Cooper et al. · Genes & Development · 2002 · 1.5K citations · Full text

, , +13