Concepedia

Absorption, Distribution, Metabolism, and Elimination of the Direct Renin Inhibitor Aliskiren in Healthy Volunteers

Felix Waldmeier, Ulrike Glaenzel, B. Wirz, Lukas Oberer, Dietmar G. Schmid, Michael Seiberling, Jessica Valencia, Gilles‐Jacques Rivière, Peter End, Sujata Vaidyanathan

Drug Metabolism and Disposition · 2007 · 127 citations · 18 references

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18

Global burden of hypertension: analysis of worldwide data

Patricia M. Kearney, Megan Whelton, Kristi Reynolds et al. · The Lancet · 2005 · 7.7K citations

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Aliskiren, a Novel Orally Effective Renin Inhibitor, Provides Dose-Dependent Antihypertensive Efficacy and Placebo-Like Tolerability in Hypertensive Patients

Alan H. Gradman, Roland E. Schmieder, R. Lins et al. · Circulation · 2005 · 524 citations

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Structure-based design of aliskiren, a novel orally effective renin inhibitor

Jeanette M. Wood, Jürgen Maibaum, Joseph Rahuel et al. · Biochemical and Biophysical Research Communications · 2003 · 503 citations

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Blood Pressure Lowering in Essential Hypertension With an Oral Renin Inhibitor, Aliskiren

Alice Stanton, C. Jensen, Juerg Nussberger et al. · Hypertension · 2003 · 341 citations

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THE PREPARATION, PURIFICATION, AND AMINO ACID SEQUENCE OF A POLYPEPTIDE RENIN SUBSTRATE

Leonard T. Skeggs, Joseph R. Kahn, Kenneth E. Lentz et al. · The Journal of Experimental Medicine · 1957 · 318 citations · Full text

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