Concepedia

The Asparaginyl Hydroxylase Factor Inhibiting HIF-1α Is an Essential Regulator of Metabolism

Na Zhang, Zhenxing Fu, Sarah Linke, Johana Chicher, Jeffrey J. Gorman, DeeAnn Visk, Gabriel G. Haddad, Lorenz Poellinger, Daniel J. Peet, Frank L. Powell,

Cell Metabolism · 2010 · 252 citations · 33 references

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33

FIH-1 is an asparaginyl hydroxylase enzyme that regulates the transcriptional activity of hypoxia-inducible factor

David Lando, Daniel J. Peet, Jeffrey J. Gorman et al. · Genes & Development · 2002 · 1.5K citations · Full text

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FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity

Patrick C. Mahon, Kiichi Hirota, Gregg L. Semenza · Genes & Development · 2001 · 1.4K citations · Full text

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Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.

Merja Lakso, José G. Pichel, James Gorman et al. · Proceedings of the National Academy of Sciences · 1996 · 1.1K citations · Full text

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Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1

Gregg L. Semenza · Physiology · 2009 · 926 citations

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Complementary action of the PGC-1 coactivators in mitochondrial biogenesis and brown fat differentiation

Marc Uldry, Wenli Yang, Julie St‐Pierre et al. · Cell Metabolism · 2006 · 639 citations · Full text

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