Patrick C. Mahon

FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity

Patrick C. Mahon, Kiichi Hirota, Gregg L. Semenza · Genes & Development · 2001 · 1.4K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

HER2 (neu) Signaling Increases the Rate of Hypoxia-Inducible Factor 1α (HIF-1α) Synthesis: Novel Mechanism for HIF-1-Mediated Vascular Endothelial Growth Factor Expression

Erik Laughner, Panthea Taghavi, Kelly A. Chiles et al. · Molecular and Cellular Biology · 2001 · 1.3K citations · Full text

Life Sciences, Cell Biology, Oncology +17

Periostin promotes invasiveness and resistance of pancreatic cancer cells to hypoxia-induced cell death: role of the β4 integrin and the PI3k pathway

Patrick Baril, Rathi Gangeswaran, Patrick C. Mahon et al. · Oncogene · 2006 · 272 citations

Life Sciences, Cancer Biology, Cell Biology +17

OS-9 Interacts with Hypoxia-Inducible Factor 1α and Prolyl Hydroxylases to Promote Oxygen-Dependent Degradation of HIF-1α

Jin Hyen Baek, Patrick C. Mahon, Jane C Oh et al. · Molecular Cell · 2005 · 221 citations · Full text

Life Sciences, Biochemistry, Cell Biology +14

Intrinsic Chemoresistance to Gemcitabine Is Associated with Decreased Expression of BNIP3 in Pancreatic Cancer

Masanori Akada, Tatjana Crnogorac‐Jurcevic, Samuel Lattimore et al. · Clinical Cancer Research · 2005 · 180 citations · Full text

Medicine, Oncology, Pharmacology +17