Kiichi Hirota

FIH-1: a novel protein that interacts with HIF-1α and VHL to mediate repression of HIF-1 transcriptional activity

Patrick C. Mahon, Kiichi Hirota, Gregg L. Semenza · Genes & Development · 2001 · 1.4K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

AP-1 transcriptional activity is regulated by a direct association between thioredoxin and Ref-1

Kiichi Hirota, Minoru Matsui, Satoshi Iwata et al. · Proceedings of the National Academy of Sciences · 1997 · 839 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Insulin-like Growth Factor 1 Induces Hypoxia-inducible Factor 1-mediated Vascular Endothelial Growth Factor Expression, Which is Dependent on MAP Kinase and Phosphatidylinositol 3-Kinase Signaling in Colon Cancer Cells

Ryo Fukuda, Kiichi Hirota, Lee M. Ellis et al. · Journal of Biological Chemistry · 2002 · 822 citations · Full text

Life Sciences, Cell Biology, Oncology +17

Identification of Thioredoxin-binding Protein-2/Vitamin D3 Up-regulated Protein 1 as a Negative Regulator of Thioredoxin Function and Expression

Akira Nishiyama, Minoru Matsui, Satoshi Iwata et al. · Journal of Biological Chemistry · 1999 · 731 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +9

Correction: Corrigendum: Cancer cells that survive radiation therapy acquire HIF-1 activity and translocate toward tumour blood vessels

Hiroshi Harada, Masahiro Inoue, Satoshi Itasaka et al. · Nature Communications · 2013 · 676 citations · Full text

Medicine, Cancer Biology, Oncology +17