In vitro molecular evolution of antibody genes mimicking receptor revision

IMGT, the international ImMunoGeneTics database

Manuel Ruiz · Nucleic Acids Research · 2000 · 876 citations · Full text

Life Sciences, Bioinformatics, Immunology +17

Diversity in the CDR3 Region of VH Is Sufficient for Most Antibody Specificities

Mark M. Davis · Immunity · 2000 · 804 citations · Full text

Pharmacy, Immunology, Molecular Biology +16

Kinetics of protein-protein association explained by Brownian dynamics computer simulation.

Scott H. Northrup, Harold Erickson · Proceedings of the National Academy of Sciences · 1992 · 584 citations

Life Sciences, Biochemistry, Biophysics +17

Frequent occurrence of deletions and duplications during somatic hypermutation: Implications for oncogene translocations and heavy chain disease

Tina Goossens, Ulf Klein, Ralf Küppers · Proceedings of the National Academy of Sciences · 1998 · 345 citations

Life Sciences, Genetics, Molecular Biology +17

Recombining germline-derived CDR sequences for creating diverse single-framework antibody libraries

Eskil Söderlind, Leif Strandberg, Pernilla Jirholt et al. · Nature Biotechnology · 2000 · 335 citations

Pharmacy, Biotechnology, Molecular Biology +14