Concepedia

Debio0932, a second-generation oral heat shock protein (HSP) inhibitor, in patients with advanced cancer—results of a first-in-man dose-escalation study with a fixed-dose extension phase

Nicolás Isambert, Jean‐Pierre Delord, Jean‐Charles Soria, Antoine Hollebecque, Carlos Gomez‐Roca, Daniela Purcea, Elisabeth Rouits, Riccardo Belli, P. Fumoleau

Annals of Oncology · 2015 · 36 citations · 15 references

DOI

Concepts

References

15

New Guidelines to Evaluate the Response to Treatment in Solid Tumors

Patrick Therasse, Susan G. Arbuck, Elizabeth A. Eisenhauer et al. · JNCI Journal of the National Cancer Institute · 2000 · 15.7K citations

, , +17

Measurement of clinical and subclinical tumour response using [18F]-fluorodeoxyglucose and positron emission tomography: review and 1999 EORTC recommendations

Helen Young, R. Baum, U. Cremerius et al. · European Journal of Cancer · 1999 · 1.7K citations · Full text

, , +11

In Vivo Function of Hsp90 Is Dependent on ATP Binding and ATP Hydrolysis

Wolfgang M.J. Obermann, Holger Sondermann, Alicia A. Russo et al. · The Journal of Cell Biology · 1998 · 597 citations · Full text

, , +18

Molecular chaperones and the stress of oncogenesis

Dick D. Mosser, Richard I. Morimoto · Oncogene · 2004 · 501 citations

, , +7

NVP-AUY922: A Novel Heat Shock Protein 90 Inhibitor Active against Xenograft Tumor Growth, Angiogenesis, and Metastasis

Suzanne A. Eccles, Andy Massey, Florence I. Raynaud et al. · Cancer Research · 2008 · 469 citations