Hypomorphic nuclear factor-κB essential modulator mutation database and reconstitution system identifies phenotypic and immunologic diversity

Epithelial NEMO links innate immunity to chronic intestinal inflammation

Arianna Nenci, Christoph Becker, Andy Wullaert et al. · Nature · 2007 · 1.1K citations · Full text

Life Sciences, Cell Biology, Immunology +14

X-linked anhidrotic ectodermal dysplasia with immunodeficiency is caused by impaired NF-κB signaling

Rainer Döffinger, Asma Smahi, Christine Bessia et al. · Nature Genetics · 2001 · 819 citations

Life Sciences, Genetics, Molecular Genetics +13

Genomic rearrangement in NEMO impairs NF-κB activation and is a cause of incontinentia pigmenti

Asma Smahi, Nina S. Heiss, Petra Kioschis et al. · Nature · 2000 · 743 citations

Life Sciences, Genetics, Molecular Biology +11

Sensing of Lys 63-linked polyubiquitination by NEMO is a key event in NF-κB activation

Chuan-Jin Wu, Dietrich B. Conze, Tao Li et al. · Nature Cell Biology · 2006 · 599 citations

Life Sciences, Biochemistry, Molecular Biology +10

A Novel X-Linked Disorder of Immune Deficiency and Hypohidrotic Ectodermal Dysplasia Is Allelic to Incontinentia Pigmenti and Due to Mutations in IKK-gamma (NEMO)

Jonathan Zonana, Melissa E. Elder, Lynda C. Schneider et al. · The American Journal of Human Genetics · 2000 · 523 citations · Full text

Medicine, Genetics, Molecular Genetics +15