Concepedia

Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity

Pascal Descargues, Céline Deraison, Chrystelle Bonnart, Maaike Kreft, Mari Kishibe, Akemi Ishida‐Yamamoto, Peter M. Elias, Yann Barrandon, Giovanna Zambruno, Arnoud Sonnenberg,

Nature Genetics · 2004 · 377 citations · 45 references

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45

Claudin-based tight junctions are crucial for the mammalian epidermal barrier

Mikio Furuse, Masaki Hata, Kyoko Furuse et al. · The Journal of Cell Biology · 2002 · 1.5K citations · Full text

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Mutations in SPINK5, encoding a serine protease inhibitor, cause Netherton syndrome

Stéphane Chavanas, Christine Bodemer, Ariane Rochat et al. · Nature Genetics · 2000 · 845 citations

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Klf4 is a transcription factor required for establishing the barrier function of the skin

Julia A. Segre, Christoph Bauer, Elaine Fuchs · Nature Genetics · 1999 · 793 citations

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Degradation of Corneodesmosome Proteins by Two Serine Proteases of the Kallikrein Family, SCTE/KLK5/hK5 and SCCE/KLK7/hK7

Cécile Caubet, Nathalie Jonca, Maria Brattsand et al. · Journal of Investigative Dermatology · 2004 · 509 citations · Full text

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Toxin in bullous impetigo and staphylococcal scalded-skin syndrome targets desmoglein 1

Masayuki Amagai, Norihisa Matsuyoshi, Zhi Hong Wang et al. · Nature Medicine · 2000 · 492 citations

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