Pascal Descargues

Carcinoma-produced factors activate myeloid cells through TLR2 to stimulate metastasis

Sun-Hwa Kim, Hiroyuki Takahashi, Wan‐Wan Lin et al. · Nature · 2008 · 1.1K citations · Full text

Oncology, Medicine, Immunology +8

Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea

Kenshi Yamasaki, Anna Di Nardo, Antonella Bardan et al. · Nature Medicine · 2007 · 824 citations

Inflammation, Medicine, Cutaneous Biology +7

Kallikrein‐mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin

Kenshi Yamasaki, Jürgen Schauber, Alvin B. Coda et al. · The FASEB Journal · 2006 · 456 citations

Microbial Pathogens, Antimicrobial Effects, Immunology +18

Spink5-deficient mice mimic Netherton syndrome through degradation of desmoglein 1 by epidermal protease hyperactivity

Pascal Descargues, Céline Deraison, Chrystelle Bonnart et al. · Nature Genetics · 2004 · 374 citations

Signal Transduction, Signaling Pathway, Receptor Tyrosine Kinase +11

Corneodesmosomal Cadherins Are Preferential Targets of Stratum Corneum Trypsin- and Chymotrypsin-like Hyperactivity in Netherton Syndrome

Pascal Descargues, Céline Deraison, Cathérine Prost et al. · Journal of Investigative Dermatology · 2006 · 191 citations · Full text

Corneal Dystrophy, Corneodesmosomal Cadherins, Pathology +6