Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle - Concepedia

Concepedia

Publication | Open Access

Muscle-Specific IRS-1 Ser→Ala Transgenic Mice Are Protected From Fat-Induced Insulin Resistance in Skeletal Muscle

DOI Full Paper Access

120

Citations

39

References

2008

Year

Katsutaro Morino, Susanne Neschen, Stefan Bilz, Saki Sono, Dimitrios N. Tsirigotis, Richard M. Reznick, Irene K. Moore, Yoshio Nagai, Varman T. Samuel, David Sebastián,

Abstract

These data demonstrate that serine phosphorylation of IRS-1 plays an important role in mediating fat-induced insulin resistance in skeletal muscle in vivo.

References

	Year	Citations

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