David Sebastián

Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis

David Sebastián, María Isabel Hernández‐Álvarez, Jessica Segalés et al. · Proceedings of the National Academy of Sciences · 2012 · 648 citations

Mitophagy, Mitochondrial Biology, Metabolic Remodeling +24

Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance

Marc Schneeberger, Marcelo O. Dietrich, David Sebastián et al. · Cell · 2013 · 503 citations · Full text

Neuropeptides, Molecular Physiology, Neurophysiology +13

Mfn2 modulates the UPR and mitochondrial function via repression of PERK

Juan Pablo Muñoz, Saška Ivanova, Jana Sánchez et al. · The EMBO Journal · 2013 · 432 citations · Full text

Mitophagy, Signal Transduction, Mitochondrial Function +6

Mfn2 deficiency links age‐related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway

David Sebastián, Eleonora Sorianello, Jessica Segalés et al. · The EMBO Journal · 2016 · 371 citations · Full text

Cell Autophagy, Mitophagy, Disease Mechanism +9

Deficient Endoplasmic Reticulum-Mitochondrial Phosphatidylserine Transfer Causes Liver Disease

María Isabel Hernández‐Álvarez, David Sebastián, Sara Vives et al. · Cell · 2019 · 367 citations

Hepatology, Mitochondrial Function, Mitochondrial Dynamic +8