Jessica Segalés

Mitofusin 2 (Mfn2) links mitochondrial and endoplasmic reticulum function with insulin signaling and is essential for normal glucose homeostasis

David Sebastián, María Isabel Hernández‐Álvarez, Jessica Segalés et al. · Proceedings of the National Academy of Sciences · 2012 · 648 citations

Mitophagy, Mitochondrial Biology, Metabolic Remodeling +24

Mfn2 deficiency links age‐related sarcopenia and impaired autophagy to activation of an adaptive mitophagy pathway

David Sebastián, Eleonora Sorianello, Jessica Segalés et al. · The EMBO Journal · 2016 · 371 citations · Full text

Cell Autophagy, Mitophagy, Disease Mechanism +9

Senescence atlas reveals an aged-like inflamed niche that blunts muscle regeneration

Victoria Moiseeva, Andrés Cisneros, Valentina Sica et al. · Nature · 2022 · 327 citations · Full text

Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy

Xiaotong Hong, Joan Isern, Silvia Campanario et al. · Cell stem cell · 2022 · 187 citations · Full text

Regenerative Medicine, Regenerative Competence, Mitophagy +9

Sestrin prevents atrophy of disused and aging muscles by integrating anabolic and catabolic signals

Jessica Segalés, Eusebio Perdiguero, Antonio L. Serrano et al. · Nature Communications · 2020 · 143 citations · Full text