Concepedia

Up-regulation of Programmed Cell Death 1 Ligand 1 on Neutrophils May Be Involved in Sepsis-induced Immunosuppression

Jiafeng Wang, Jinbao Li, Yan-jun Zhao, Wenjing Yi, Jinjun Bian, Xiaojian Wan, Keming Zhu, Xiaoming Deng

Anesthesiology · 2014 · 125 citations · 26 references

DOIFull text

Open access

Abstract

PD-L1 is up-regulated on neutrophils during sepsis, which may be related to sepsis-induced immunosuppression.

References

26

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A subset of neutrophils in human systemic inflammation inhibits T cell responses through Mac-1

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, , +6