Three Pairs of Protease-Serpin Complexes Cooperatively Regulate the Insect Innate Immune Responses

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein

Tatiana Michel, Jean‐Marc Reichhart, Jules A. Hoffmann et al. · Nature · 2001 · 778 citations

Virulence Factor, Pathogenesis, Immunology +7

Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors

Marie Gottar, Vanessa Gobert, Alexey A. Matskevich et al. · Cell · 2006 · 502 citations · Full text

Biology, Diagnostic Mycology, Dual Detection +8

Constitutive Activation of Toll-Mediated Antifungal Defense in Serpin-Deficient <i>Drosophila</i>

Elena A. Levashina, Emma Langley, Clare Green et al. · Science · 1999 · 435 citations

Toll-like Receptors, Molecular Immunology, Constitutive Activation +15

An Immune-Responsive Serpin Regulates the Melanization Cascade in Drosophila

Ennio De Gregorio, Sung‐Jun Han, Won‐Jae Lee et al. · Developmental Cell · 2002 · 347 citations · Full text

Immune-responsive Serpin, Developmental Genetics, Genetics +3

A serpin mutant links Toll activation to melanization in the host defence of Drosophila

Petros Ligoxygakis · The EMBO Journal · 2002 · 286 citations · Full text

Biology, Host Defence, Natural Sciences +9