Jules A. Hoffmann

The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults

Bruno Lemaître, Émmanuelle Nicolas, Lydia Michaut et al. · Cell · 1996 · 3.9K citations · Full text

Biology, Potent Antifungal Response, Natural Sciences +10

Immunity-Related Genes and Gene Families in <i>Anopheles gambiae</i>

George K. Christophides, Evgeny M. Zdobnov, Carolina Barillas‐Mury et al. · Science · 2002 · 960 citations

Excessive Gene Expansions, Gene Families, Genetics +16

Drosophila Toll is activated by Gram-positive bacteria through a circulating peptidoglycan recognition protein

Tatiana Michel, Jean‐Marc Reichhart, Jules A. Hoffmann et al. · Nature · 2001 · 778 citations

Virulence Factor, Pathogenesis, Immunology +7

The Jak-STAT signaling pathway is required but not sufficient for the antiviral response of drosophila

Catherine Dostert, Emmanuelle Jouanguy, Phil Irving et al. · Nature Immunology · 2005 · 643 citations

Signal Transduction, Molecular Virology, Immunology +6

A recessive mutation, immune deficiency (imd), defines two distinct control pathways in the Drosophila host defense.

Bruno Lemaître, Elisabeth KROMER‐METZGER, Lydia Michaut et al. · Proceedings of the National Academy of Sciences · 1995 · 623 citations · Full text

Microbial Pathogens, Genetics, Innate Immune System +19