Concepedia

CEP-26401 (Irdabisant), a Potent and Selective Histamine H3 Receptor Antagonist/Inverse Agonist with Cognition-Enhancing and Wake-Promoting Activities

Rita Raddatz, Robert L. Hudkins, Joanne R. Mathiasen, John A. Gruner, Dorothy G. Flood, Lisa D. Aimone, Siyuan Le, Hervé Schaffhauser, Emir Duzic, Maciej Ga̧sior,

Journal of Pharmacology and Experimental Therapeutics · 2011 · 58 citations · 34 references

DOI

Concepts

References

34

Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptor

Jean‐Michel Arrang, M. Garbarg, Jean‐Charles Schwartz · Nature · 1983 · 1.6K citations

, , +14

Highly potent and selective ligands for histamine H3-receptors

J.M. Arrang, M. Garbarg, J.-C. Lancelo et al. · Nature · 1987 · 902 citations

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Cloning and Functional Expression of the Human Histamine H<sub>3</sub>Receptor

Timothy W. Lovenberg, Barbara Roland, Sandy J. Wilson et al. · Molecular Pharmacology · 1999 · 700 citations · Full text

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Institute of Laboratory Animal Resources.

Thomas L. Wolfle · 1995 · 618 citations

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High constitutive activity of native H3 receptors regulates histamine neurons in brain

Séverine Morisset‐Lopez, A. Rouleau, Xavier Ligneau et al. · Nature · 2000 · 463 citations

, , +11