Concepedia

SCD1 negatively regulates autophagy-induced cell death in human hepatocellular carcinoma through inactivation of the AMPK signaling pathway

Guangming Huang, Qinghu Jiang, Can Cai, Wei Shen

Cancer Letters · 2014 · 111 citations · 40 references

DOI

Concepts

References

40

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

Joungmok Kim, Mondira Kundu, Benoı̂t Viollet et al. · Nature Cell Biology · 2011 · 7K citations · Full text

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p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death

Geir Bjørkøy, Trond Lamark, Andreas Brech et al. · The Journal of Cell Biology · 2005 · 3.3K citations · Full text

, , +15

The AMPK signalling pathway coordinates cell growth, autophagy and metabolism

Maria M. Mihaylova, Reuben J. Shaw · Nature Cell Biology · 2011 · 2.9K citations · Full text

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Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy

Daniel F. Egan, David B. Shackelford, Maria M. Mihaylova et al. · Science · 2010 · 2.6K citations

, , +17

Promotion of tumorigenesis by heterozygous disruption of the beclin 1 autophagy gene

Xueping Qu, Jie Yu, Govind Bhagat et al. · Journal of Clinical Investigation · 2003 · 2.2K citations · Full text

, , +15