A truncation mutant of Csf3r cooperates with PML-RARα to induce acute myeloid leukemia in mice

Single Cell Profiling of Potentiated Phospho-Protein Networks in Cancer Cells

Jonathan M. Irish, Randi Hovland, Peter O. Krutzik et al. · Cell · 2004 · 687 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Flt3 mutations from patients with acute myeloid leukemia induce transformation of 32D cells mediated by the Ras and STAT5 pathways

Masao Mizuki, R. Fenski, Hartmut Halfter et al. · Blood · 2000 · 581 citations

Medicine, Genetics, Molecular Biology +9

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

Fumihiko Hayakawa, Masayuki Towatari, Hitoshi Kiyoi et al. · Oncogene · 2000 · 576 citations

Life Sciences, Cell Biology, Genetics +8

A randomized controlled phase III trial of recombinant human granulocyte colony-stimulating factor (filgrastim) for treatment of severe chronic neutropenia

DC Dale, MA Bonilla, MW Davis et al. · Blood · 1993 · 477 citations · Full text

Life Sciences, Hematology, Immunology +13

Mutations in the Gene for the Granulocyte Colony-Stimulating–Factor Receptor in Patients with Acute Myeloid Leukemia Preceded by Severe Congenital Neutropenia

Fan Dong, Russell K. Brynes, Nicola Tidow et al. · New England Journal of Medicine · 1995 · 471 citations · Full text

Life Sciences, Genetics, Hematology +16